Perform cell culture and molecular biology procedures including DNA or RNA isolation, PCR, molecular cloning and Western blotting. Execute high throughput single cell genomics and functional CRISPR screens in cancer cell lines. Investigate and develop new methods and technologies for project advancement. Plan experiments, together with your supervisor, to address specific

The Broad Institute of MIT & Harvard is looking for a Research Associate II to join the therapeutic group at the Stanley Center for Psychiatric Research. The mission of the Stanley Center is to improve the lives of patients suffering from serious mental illnesses, through groundbreaking basic and translational research. Based on unprecedented insights into the genetic bas

Apply computational methods to discover and analyze structural variation from long read sequencing of large human genome cohorts. Perform quality control assessments with a deep understanding of the data and the underlying biology. Develop new computational methods and improve existing methods for genomics analyses. Present results to both computational and non computatio

for the role Work in close collaboration with multiple labs, most especially those of Drs. Macosko and Stevens, to develop and execute experimental plans; Directly supervise a multidisciplinary team of researchers responsible for generating foundational datasets for the initiative; Lead regular meetings with industry partners participating in the new initiative; Manage hig

Contribute to high throughput data production efforts by generating large scale cell based assay data in a fast paced, production oriented setting. Perform cell culture on up to 20 cell lines in parallel, with accurate monitoring for contamination and cell line fidelity as well as performing standard molecular biology procedures. Support in maintaining high quality data p

Establish procedures for tissue culture based experiments that involve measuring different phenotypic readouts (RNA, protein, reporter, viability, etc.) following chemical and genetic perturbations in both cell lines and primary iPSC derived neuronal cell models. Execute high throughput genome scale CRISPR modifier screens. Execute high throughput chemical modifier screen

Extensive experience in mammalian tissue culture. Establish procedures for tissue culture based experiments that involve measuring different phenotypic readouts (RNA, protein, reporter, viability, etc.) following chemical and genetic perturbations in both cell lines and primary patient derived cell models. Develop novel functional genomic, phenotypic, and biochemical assa

The Clinical Research Coordinator (CRC) will perform research activities using approved techniques. The CRC procures, processes and ships research specimens and conducts patient recruitment, administers questionnaires and obtains informed consents, abstracts medical records, maintains patient databases, enters data into sponsor specific electronic data capture forms and p

The Research Assistant's primary responsibility will be to support research and evaluation activities under the direct supervision of the Research Manager. 1. Provide assistance on day to day operations of research activities as per study guidelines and protocols, including, but not limited, to preparing study materials for use in the field, such as printing and assemblin

The Research Assistant's primary responsibility will be to support research and evaluation activities under the direct supervision of the Research Manager. 1. Provide assistance on day to day operations of research activities as per study guidelines and protocols, including, but not limited, to preparing study materials for use in the field, such as printing and assemblin

The Research Assistant's primary responsibility will be to support research and evaluation activities under the direct supervision of the Research Manager. 1. Provide assistance on day to day operations of research activities as per study guidelines and protocols, including, but not limited, to preparing study materials for use in the field, such as printing and assemblin

We are seeking a highly qualified and motivated Bioinformaticist or computational biologist to join our collaborative teams in the Ocular Genomics Institute and the Department of Ophthalmology at Massachusetts Eye and Ear (MEE), Harvard Medical School, to work on innovative projects that combine human genetics and functional genomics to uncover novel causal mechanisms for

Please note, the functions below are representative of major duties that are typically associated with these positions. Specific responsibilities may vary based upon departmental needs. Similarly, not all duties that have been outlined will be assigned to each position. Study Start Up Oversight of the clinical trials start up process from receipt of proposal materials, pr

Responsibilities comprise, but are not limited to Assists senior lab personnel with genetic manipulation of normal and cancer cells. Patient sample handling (e.g. blood, tissue) and training on microfluidic devices will also be part of the work. Techniques used will include PCR, Western blotting, reporter assays, protein assays, plasmid construction and/or mutagenesis, ce

Please note, the functions below are representative of major duties that are typically associated with these positions. Specific responsibilities may vary based upon departmental needs. Similarly, not all duties that have been outlined will be assigned to each position. Receiving and processing HIV+ samples, following established standard operation procedures and biosafet